Active Ingredient: Etravirine
Etravirine, in combination with a boosted protease inhibitor and other antiretroviral medicinal products, is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in antiretroviral treatment-experienced paediatric patients from 6 years of age.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
200 - 400 mg
From 100 To 200 mg 2 time(s) per day every day
The recommended dose of etravirine for paediatric patients (6 years to less than 18 years of age and weighing at least 16 kg) is based on body weight (see table below). Etravirine tablet(s) should be taken orally, following a meal.
Recommended dose of etravirine for paediatric patients 6 years to less than 18 years of age:
| Body weight | Dose | Tablets |
|---|---|---|
| ≥16 to <20 kg | 100 mg twice daily | four 25 mg tablets twice daily or one 100 mg tablet twice daily |
| ≥20 to <25 kg | 125 mg twice daily | five 25 mg tablets twice daily or one 100 mg tablet and one 25 mg tablet twice daily |
| ≥25 to <30 kg | 150 mg twice daily | six 25 mg tablets twice daily or one 100 mg tablet and two 25 mg tablets twice daily |
| ≥30 kg | 200 mg twice daily | eight 25 mg tablets twice daily or two 100 mg tablets twice daily or one 200 mg tablet twice daily |
Missed dose
If the patient misses a dose of etravirine within 6 hours of the time it is usually taken, the patient should take it following a meal as soon as possible and then take the next dose at the regularly scheduled time. If a patient misses a dose by more than 6 hours of the time it is usually taken, the patient should not take the missed dose and simply resume the usual dosing schedule.
If a patient vomits within 4 hours of taking the medicine, another dose of etravirine should be taken following a meal as soon as possible. If a patient vomits more than 4 hours after taking the medicine, the patient does not need to take another dose until the next regularly scheduled time.
Take after meal.
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