Active Ingredient: Pantoprazole
For this indication, competent medicine agencies globally authorize below treatments:
Oral
80 - 80 mg
From 40 To 40 mg 2 time(s) per day every day
In H. pylori positive patients with gastric and duodenal ulcers, eradication of the germ by a combination therapy should be achieved. Considerations should be given to official local guidance (e.g. national recommendations) regarding bacterial resistance and the appropriate use and prescription of antibacterial agents. Depending upon the resistance pattern, the following combinations can be recommended for the eradication of H. pylori:
a) Twice daily 40 mg pantoprazole
+ twice daily 1000 mg amoxicillin
+ twice daily 500 mg clarithromycin
b) Twice daily 40 mg pantoprazole
+ twice daily 400-500 mg metronidazole (or 500 mg tinidazole)
+ twice daily 250-500 mg clarithromycin
c) Twice daily 40 mg pantoprazole
+ twice daily 1000 mg amoxicillin
+ twice daily 400-500 mg metronidazole (or 500 mg tinidazole)
In combination therapy for eradication of H. pylori infection, the second pantoprazole tablet should be taken 1 hour before the evening meal. The combination therapy is implemented for 7 days in general and can be prolonged for a further 7 days to a total duration of up to two weeks. If, to ensure healing of the ulcers, further treatment with pantoprazole is indicated, the dose recommendations for duodenal and gastric ulcers should be considered.
It should be swallowed 1 hour before a meal with some water.
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