Infection caused by Zaire ebolavirus

Active Ingredient: Ansuvimab

Indication for Ansuvimab

Population group: only minors (0 - 18 years old) , adults (18 years old or older)
Therapeutic intent: Curative procedure

Ansuvimab is indicated for the treatment of infection caused by Zaire ebolavirus in adult and pediatric patients, including neonates born to a mother who is RT-PCR positive for Zaire ebolavirus infection.

Limitations of use

The efficacy of ansuvimab has not been established for other species of the Ebolavirus and Marburgvirus genera.

Zaire ebolavirus can change over time, and factors such as emergence of resistance, or changes in viral virulence could diminish the clinical benefit of antiviral drugs. Consider available information on drug susceptibility patterns for circulating Zaire ebolavirus strains when deciding whether to use ansuvimab.

For this indication, competent medicine agencies globally authorize below treatments:

50 mg/kg once

For:

Dosage regimens

Intravenous, 50 milligrams ansuvimab per kilogram of body weight, one dose.

Detailed description

The recommended dosage of ansuvimab is 50 mg/kg administered as a single intravenous (IV) infusion over 60 minutes.

Active ingredient

Ansuvimab

Ansuvimab is a recombinant human monoclonal antibody with antiviral activity against Zaire ebolavirus.

Read more about Ansuvimab

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