Active Ingredient: Ertugliflozin
Ertugliflozin is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise:
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, between 5 milligrams ertugliflozin and 15 milligrams ertugliflozin, once daily at morning.
The recommended starting dose of ertugliflozin is 5 mg once daily. In patients tolerating ertugliflozin 5 mg once daily, the dose can be increased to 15 mg once daily if additional glycaemic control is needed.
When ertugliflozin is used in combination with insulin or an insulin secretagogue, a lower dose of insulin or the insulin secretagogue may be required to reduce the risk of hypoglycaemia.
In patients with volume depletion, correcting this condition prior to initiation of ertugliflozin is recommended.
If a dose is missed, it should be taken as soon as the patient remembers. Patients should not take two doses of ertugliflozin on the same day.
No dose adjustment of ertugliflozin is recommended based on age. Renal function and risk of volume depletion should be taken into account.
Should be taken orally once daily in the morning, with or without food.
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