Juvenile idiopathic arthritis, discoid and systemic lupus erythematosus

Active Ingredient: Hydroxychloroquine

Indication for Hydroxychloroquine

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Treatment of juvenile idiopathic arthritis (in combination with other therapies) , discoid and systemic lupus erythematosus.

For this indication, competent medicine agencies globally authorize below treatments:

3-6.5 mg/kg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

3 - 6.5 mg per kg of body weight

Dosage regimen

From 1.5 To 3.25 mg per kg of body weight 2 time(s) per day every day

Detailed description

The minimum effective dose should be employed and should not exceed 6.5 mg/kg/day based on ideal body weight. The 200 mg tablet is therefore not suitable for use in children with an ideal body weight of less than 31kg.

Hydroxychloroquine is cumulative in action and will require several weeks to exert its beneficial effects, whereas minor side effects may occur relatively early. For rheumatic disease treatment should be discontinued if there is no improvement by 6 months. In light-sensitive diseases, treatment should only be given during periods of maximum exposure to light.

Dosage considerations

Each dose should be taken with a meal or glass of milk.

Active ingredient

Hydroxychloroquine

Hydroxychloroquine is a antimalarial agent with have several pharmacological actions which may be involved in their therapeutic effect in the treatment of rheumatic disease, but its role is not known.

Read more about Hydroxychloroquine

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