Moderate to severe manic episodes associated with bipolar disorders

Active Ingredient: Risperidone

Indication for Risperidone

Population group: only adults (18 - 65 years old)

Risperidone is indicated for the treatment of moderate to severe manic episodes associated with bipolar disorders.

For this indication, competent medicine agencies globally authorize below treatments:

2-6 mg once daily

Route of admnistration

Oral

Defined daily dose

2 - 6 mg

Dosage regimen

From 2 To 6 mg once every day

Loading dose

2 mg

Detailed description

Risperidone should be administered on a once daily schedule, starting with 2mg risperidone. Dosage adjustments, if indicated, should occur at intervals of not less than 24 hours and in dosage increments of 1mg per day. Risperidone can be administered in flexible doses over a range of 1 to 6 mg per day to optimize each patient’s level of efficacy and tolerability. Daily doses over 6 mg risperidone have not been investigated in patients with manic episodes.

As with all symptomatic treatments, the continued use of Risperidone must be evaluated and justified on an ongoing basis.

Dosage considerations

Risperidone is for oral use. Food does not affect the absorption of Risperidone.

Upon discontinuation, gradual withdrawal is advised. Acute withdrawal symptoms, including nausea, vomiting, sweating, and insomnia have very rarely been described after abrupt cessation of high doses of antipsychotic medicines. Recurrence of psychotic symptoms may also occur, and the emergence of involuntary movement disorders (such as akathisia, dystonia and dyskinesia) has been reported.

Active ingredient

Risperidone

Risperidone is a selective monoaminergic antagonist with unique properties. Although risperidone is a potent D2 antagonist, which is considered to improve the positive symptoms of schizophrenia, it causes less depression of motor activity and induction of catalepsy than classical antipsychotics.

Read more about Risperidone

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