Amoebic involvement of the liver

Active Ingredient: Tinidazole

Indication for Tinidazole

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

1,500-2,000 mg once daily

Route of admnistration

Oral

Defined daily dose

1,500 - 2,000 mg

Dosage regimen

From 1,500 To 2,000 mg once every day

Detailed description

Total dosage varies from 4.5 to 12g, depending on the virulence of the Entamoeba histolytica.

For amoebic involvement of the liver, the aspiration of pus may be required in addition to therapy with tinidazole.

Initiate treatment with 1.5 to 2g as a single oral daily dose for three days. Occasionally when a three day course is ineffective, treatment may be continued for up to six days.

Dosage considerations

It should be taken during or after a meal.

Active ingredient

Tinidazole

Tinidazole is active against both protozoa and obligate anaerobic bacteria. The activity against protozoa involves Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia. The mode of action of tinidazole against anaerobic bacteria and protozoa involves penetration of the drug into the cell of the micro-organism and subsequent damage of DNA strands or inhibition of their synthesis.

Read more about Tinidazole

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