Active Ingredient: Zidovudine
Zidovudine chemoprophylaxis is indicated for primary prophylaxis of HIV infection in newborn infants.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 2 milligrams zidovudine per kilogram of body weight, once every 6 hours, over the duration of 6 weeks.
Neonates should be given 2 mg/kg bodyweight orally every 6 hours starting within 12 hours after birth and continuing until 6 weeks-old.
For:
Intravenous, 1.5 milligrams zidovudine per kilogram of body weight, once every 6 hours.
Infants unable to receive oral dosing should be given zidovudine intravenously at 1.5 mg/kg bodyweight infused over 30 minutes every 6 hours.
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