Moderate to severe chronic hand eczema (CHE)

Active Ingredient: Delgocitinib

Indication for Delgocitinib

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Delgocitinib is indicated for the treatment of moderate to severe chronic hand eczema (CHE) in adults for whom topical corticosteroids are inadequate or inappropriate.

For this indication, competent medicine agencies globally authorize below treatments:

A thin layer of delgocitinib every 12 h

For:

Dosage regimens

Cutaneous, 1 spreads delgocitinib, once every 12 hours.

Detailed description

A thin layer of delgocitinib should be applied twice daily to the affected skin of the hands and wrists until the skin is clear or almost clear. It is recommended to apply the cream at regular intervals, approximately 12 hours apart.

In the event of recurrence of the signs and symptoms of CHE (flares), twice daily treatment of the affected areas should be re-initiated as needed.

Treatment should be discontinued if no improvement is seen after 12 weeks of continuous treatment.

Missed dose

If an application is missed, the cream should be applied as soon as possible. Thereafter, applications should be resumed at the regular scheduled time.

Dosage considerations

Patients should avoid applying other topical products immediately before and after application of delgocitinib. Co-application with emollients within 2 hours before and after application of delgocitinib has not been studied.

If someone else applies the cream to the patient, they should be instructed to wash their hands after application.

Contact with eyes, mouth, or other mucous membranes should be avoided. If contact with mucous membranes occurs, rinse thoroughly with water.

Active ingredient

Delgocitinib

Delgocitinib is a pan Janus kinase (JAK) inhibitor that targets the activity of all four members of the JAK family of enzymes consisting of JAK1, JAK2, JAK3, and tyrosine kinase 2 (TYK2) in a concentration dependent manner.

Read more about Delgocitinib

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