Paroxysmal supraventricular tachycardias, Wolff-Parkinson-White Syndrome

Active Ingredient: Adenine Deoxy Nucleoside

Indication for Adenine Deoxy Nucleoside

Population group: only adults (18 years old or older)

Rapid conversion to a normal sinus rhythm of paroxysmal supraventricular tachycardias, including those associated with accessory by-pass tracts (Wolff-Parkinson-White Syndrome).

For this indication, competent medicine agencies globally authorize below treatments:

Initial dose 3mg, Second dose 6mg, Third dose 12mg

Route of admnistration

Intravenous

Defined daily dose

3 - 21 mg

Dosage regimen

From 3 To 21 mg once every day

Loading dose

3 mg

Detailed description

Initial dose: 3mg given as a rapid intravenous bolus (over 2 seconds).

Second dose: If the first dose does not result in elimination of the supraventricular tachycardia within 1 to 2 minutes, 6mg should be given also as a rapid intravenous bolus.

Third dose: If the second dose does not result in elimination of the supraventricular tachycardia within 1 to 2 minutes. 12mg should be given also as a rapid intravenous bolus.

Additional or higher doses are not recommended.

Dosage considerations

Adenocor should only be used when facilities exist for cardiac monitoring.

Active ingredient

Adenine Deoxy Nucleoside

Adenosine is a purine nucleoside which is present in all cells of the body. Animal pharmacology studies have in several species shown that adenosine has a negative dromotropic effect on the atrioventricular (AV) node.

Read more about Adenine Deoxy Nucleoside

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