Active Ingredient: Bazedoxifene
Bazedoxifene is indicated for the treatment of postmenopausal osteoporosis in women at increased risk of fracture. A significant reduction in the incidence of vertebral fractures has been demonstrated; efficacy on hip fractures has not been established.
When determining the choice of bazedoxifene or other therapies, including oestrogens, for an individual postmenopausal woman, consideration should be given to menopausal symptoms, effects on uterine and breast tissues, and cardiovascular risks and benefits.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 20 milligrams bazedoxifene, once daily.
The recommended dose is 20 mg once daily, at any time of day, with or without food.
Doses higher than 20 mg are not recommended because there is no demonstrable increased efficacy and higher doses may be associated with additional risk.
Supplemental calcium and/or vitamin D should be added to the diet if daily intake is inadequate.
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