Febrile neutropenia

Active Ingredient: Eflapegrastim

Indication for Eflapegrastim

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Eflapegrastim is indicated to decrease the incidence of infection, as manifested by febrile neutropenia, in adult patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with clinically significant incidence of febrile neutropenia.

Limitations of use:

Eflapegrastim is not indicated for the mobilization of peripheral blood progenitor cells for hematopoietic stem cell transplantation.

For this indication, competent medicine agencies globally authorize below treatments:

13.2 mg once per chemotherapy cycle

For:

Dosage regimens

Subcutaneous, 13.2 milligrams eflapegrastim, one dose.

Detailed description

The recommended dosage of eflapegrastim is a single subcutaneous injection of 13.2 mg administered once per chemotherapy cycle. Administer approximately 24 hours after cytotoxic chemotherapy. Do not administer within the period from 14 days before to 24 hours after administration of cytotoxic chemotherapy.

Active ingredient

Eflapegrastim

Eflapegrastim-xnst is a recombinant human granulocyte growth factor that binds to G-CSF receptors on myeloid progenitor cells and neutrophils, triggering signaling pathways that control cell differentiation, proliferation, migration and survival. Eflapegrastim-xnst has been shown to elevate neutrophil counts in healthy subjects and in cancer patients.

Read more about Eflapegrastim

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