Active Ingredient: Risankizumab
Risankizumab is indicated for the treatment of adult patients with moderately to severely active Crohn’s disease who have had an inadequate response to, lost response to, or were intolerant to conventional therapy or a biologic therapy.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intravenous, 600 milligrams risankizumab, once every 4 weeks, 3 doses in total, over the duration of 12 weeks. Afterwards, subcutaneous, 360 milligrams risankizumab, once every 8 weeks.
The recommended dose is 600 mg administered by intravenous infusion at week 0, week 4, and week 8, followed by 360 mg administered by subcutaneous injection at week 12, and every 8 weeks thereafter. Consideration should be given to discontinuing treatment in patients who have shown no evidence of therapeutic benefit by week 24.
If a dose is missed, the dose should be administered as soon as possible. Thereafter, dosing should be resumed at the regular scheduled time.
Intravenous infusion: The 600 mg dose should be administered over at least one hour.
Subcutaneous injection: The injection should be administered in the thigh or abdomen. Risankizumab should not be injected into areas where the skin is tender, bruised, erythematous, indurated or damaged.
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