Ankylosing spondylitis

Active Ingredient: Celecoxib

Indication for Celecoxib

Population group: only adults (18 years old or older)

Celecoxib is indicated in adults for the symptomatic relief in the treatment of ankylosing spondylitis.

For this indication, competent medicine agencies globally authorize below treatments:

200-400 mg in 1-2 divided doses daily

Route of admnistration

Oral

Defined daily dose

200 - 400 mg

Dosage regimen

From 100 To 200 mg 2 time(s) per day every day

Detailed description

The recommended daily dose is 200 mg taken once daily or in two divided doses. In a few patients, with insufficient relief from symptoms, an increased dose of 400 mg once daily or in two divided doses may increase efficacy. In the absence of an increase in therapeutic benefit after two weeks, other therapeutic options should be considered.

Dosage considerations

Celecoxib may be taken with or without food.

Active ingredient

Celecoxib

Celecoxib is an oral, selective, cyclooxygenase-2 (COX-2) inhibitor within the clinical dose range (200-400 mg daily). No statistically significant inhibition of COX-1 (assessed as ex vivo inhibition of thromboxane B2 [TxB2] formation) was observed in this dose range in healthy volunteers.

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