Active Ingredient: Chloroprocaine
For this indication, competent medicine agencies globally authorize below treatments:
For:
Perineural, between 400 milligrams chloroprocaine and 600 milligrams chloroprocaine, one dose.
Posology must be established on an individual basis in accordance with the characteristics of the specific case. When determining the dose, the patient’s physical condition and the concomitant administration of other medicinal products should be taken into consideration.
The dose administered varies with the anaesthetic procedure, the vascularity of the tissues, the depth of anaesthesia and degree of muscle relaxation required, the duration of anaesthesia desired, and the physical condition of the patient.
The following table is a guide to dosage for the more commonly used blocks. The smallest dose required to produce an effective block should be used.
| Anaesthetic Procedure | Volume (ml) | Total dose (mg) |
|---|---|---|
| Major Nerve Blocks* Axillary block Brachial plexus block Femoral block Sciatic block | 15-40 20 30-40 15-30 20-30 | 300-800 400 600-800 300-600 400-600 |
| Minor Nerve Blocks Peribulbar block Infraorbital block | 0.5-5 5 0.5-1 | 10-100 100 10-20 |
* With regard to major nerve block, only for axillary block a dose recommendation can be given. There is presently no experience of specific dose recommendations for other blocks and the posology must be established on an individual basis
The maximum recommended dose in adults is 11 mg/kg, not to exceed a maximum total dose of 800mg (=40ml) of chloroprocaine hydrochloride.
The duration of action is dose-dependent.
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