Active Ingredient: Suxamethonium
Suxamethonium is a short acting depolarising neuromuscular blocking agent for producing muscular relaxation during anaesthesia. It is used in anaesthesia as a muscle relaxant to facilitate endotracheal intubation, mechanical ventilation and a wide range of surgical and obstetric procedures.
It is also used to reduce the intensity of muscle contractions associated with Pharmacologically or electrically-induced convulsions.
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
20 - 150 mg
From 20 To 150 mg once every day
The dosage for adults and children is dependent on body weight and the degree of muscular relaxation required. The usual single dose for an adult is in the range of 20 to 100mg intravenously, depending on the patient’s body weight and the degree of muscular relaxation required. Infants and young children are relatively resistant to suxamethonium.
A suggested dose for children is in the range of 1 to 2mg/kg body weight, intravenously.
If necessary, the intramuscular route may be used and a dose up to 2.5mg/kg body weight may be given intramuscularly to adults or children to a maximum total of 150mg. For administration by continuous intravenous infusion, a 0.1 to 0.2% Solution may be used and the adult dose ranges from 2 to 5mg per minute.
Dosage requirements of suxamethonium in older patients are comparable to those for younger adults.
The elderly may be more susceptible to cardiac arrhythmias, especially if digitalis-like drugs are also being taken.
Suxamethonium is usually administered by the intravenous route. It is given intravenously after anaesthesia has been induced and should not be administered to the conscious patient. Assisted respiration is necessary.
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