Active Ingredient: Telotristat
Telotristat is indicated for the treatment of carcinoid syndrome diarrhoea in combination with somatostatin analogue (SSA) therapy in adults inadequately controlled by SSA therapy.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
750 - 750 mg
From 250 To 250 mg 3 time(s) per day every day
The recommended dose is 250 mg three times daily (tid).
Available data suggest that clinical response is usually achieved within 12 weeks of treatment. It is recommended to reassess the benefit of continued therapy in a patient not responding within this time period.
Based on the high inter-subject variability observed, accumulation in a subset of patients with carcinoid syndrome cannot be excluded. Therefore, intake of higher doses is not recommended.
Missed doses: In the event of a missed dose, patients should take their subsequent dose at the next scheduled time point. Patients should not take a double dose to make up for a missed dose.
It should be taken with food.
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