Active Ingredient: Risankizumab
Risankizumab, alone or in combination with methotrexate (MTX), is indicated for the treatment of active psoriatic arthritis in adults who have had an inadequate response or who have been intolerant to one or more disease-modifying antirheumatic drugs (DMARDs).
For this indication, competent medicine agencies globally authorize below treatments:
For:
Subcutaneous, 150 milligrams risankizumab, once every 4 weeks, 2 doses in total. Afterwards, subcutaneous, 150 milligrams risankizumab, once every 12 weeks.
The recommended dose is 150 mg administered by subcutaneous injection at week 0, week 4, and every 12 weeks thereafter.
Consideration should be given to discontinuing treatment in patients who have shown no response after 16 weeks of treatment. Some patients with initial partial response may subsequently improve with continued treatment beyond 16 weeks.
If a dose is missed, the dose should be administered as soon as possible. Thereafter, dosing should be resumed at the regular scheduled time.
The injection should be administered in the thigh or abdomen. Patients should not inject into areas where the skin is tender, bruised, erythematous, indurated, or affected by psoriasis.
Administration of risankizumab in the upper, outer arm may only be performed by a healthcare professional or caregiver.
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