Active Ingredient: Aztreonam
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intravenous, between 2 grams aztreonam and 8 grams aztreonam, divided daily, 2 to 4 doses in total. The maximum allowed total dose is 8 grams aztreonam daily.
Moderately severe systemic infections: 1 g or 2 g every 8 or 12 hours.
Severe systemic or life-threatening infections: 2 g every 6 or 8 hours.
For:
Intramuscular, between 2 grams aztreonam and 8 grams aztreonam, divided daily, 2 to 4 doses in total. The maximum allowed total dose is 8 grams aztreonam daily.
Moderately severe systemic infections: 1 g or 2 g every 8 or 12 hours.
Severe systemic or life-threatening infections: 2 g every 6 or 8 hours.
For intravenous injection
To the contents of the vial add 6 to 10 mL of Water for Injections Ph. Eur. and shake well. Slowly inject directly into the vein over a period of 3 to 5 minutes.
For intravenous infusion:
Vials: For each gram of aztreonam add at least 3 mL of Water for Injections Ph. Eur. and shake well.
Dilute this initial solution with an appropriate infusion solution to a final concentration less than 2% w/v (at least 50 mL solution per gram of aztreonam). The infusion should be administered over 20-60 minutes.
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