Advanced prostate cancer

Active Ingredient: Abarelix

Indication for Abarelix

Population group: men, only adults (18 years old or older)

Avarelix is indicated for palliative treatment of advanced prostate cancer.

For this indication, competent medicine agencies globally authorize below treatments:

100 mg once a week

Route of admnistration

Intramuscular

Defined daily dose

100 mg

Dosage regimen

100 mg once every 14 day(s) for 56 day(s)

Detailed description

The recommended dose of Abarelix is 100 mg administered intramuscularly to the buttock on Day 1, 15, 29 (week 4) and every 4 weeks thereafter.

Active ingredient

Abarelix
Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. Abarelix is primarily used in oncology to reduce the amount of testosterone made in patients with advanced symptomatic prostate cancer for which no other treatment options are available. Read more about Abarelix

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