Active Ingredient: Octreotide
For this indication, competent medicine agencies globally authorize below treatments:
Subcutaneous
0.15 - 1.5 mg
From 0.05 To 0.5 mg 3 time(s) per day every day
0.15 mg
Initially 0.05 to 0.1 mg by subcutaneous (s.c.) injection every 8 or 12 hours. Dosage adjustment should be based on monthly assessment of GH and IGF-1 levels (target: GH <2.5 ng/mL; IGF-1 within normal range) and clinical symptoms, and on tolerability. In most patients, the optimal daily dose will be 0.3 mg. A maximum dose of 1.5 mg per day should not be exceeded. For patients on a stable dose of octreotide, assessment of GH and IGF-1 should be made every 6 months.
If no relevant reduction in GH levels and no improvement in clinical symptoms have been achieved within 3 months of starting treatment with octreotide, therapy should be discontinued.
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