Active Ingredient: Naltrexone
For this indication, competent medicine agencies globally authorize below treatments:
For:
Regimen A: Oral, 25 milligrams naltrexone, once daily. Afterwards, oral, 50 milligrams naltrexone, once daily.
Regimen B: Oral, 100 milligrams naltrexone, one dose, over the duration of 2 days. Afterwards, oral, 100 milligrams naltrexone, one dose, over the duration of 2 days. Afterwards, oral, 150 milligrams naltrexone, one dose, over the duration of 3 days.
Before treatment, it has to be assured that the patient is free of opioids.
Treatment with naltrexone should only be considered for patients who have been for a sufficiently long period free of opioids.
The treatment should be initiated with low doses of naltrexone according to the treatment induction schedule.
Higher doses than 150 mg even for only one day may result in an increase in side effects and are therefore not recommended.
The recommended dose of naltrexone hydrochloride in adults is 50 mg per day.
Withdrawal symptoms may be caused by naltrexone. These may manifest after 5 minutes and least up to 48 hours. The treatment should be symptomatic and may include administration of opioids.
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