Rheumatoid arthritis, discoid and systemic lupus erythematosus, sunlight damaged skin

Active Ingredient: Hydroxychloroquine

Indication for Hydroxychloroquine

Population group: only adults (18 years old or older)

Treatment of rheumatoid arthritis, discoid and systemic lupus erythematosus, and dermatological conditions caused or aggravated by sunlight.

For this indication, competent medicine agencies globally authorize below treatments:

200-800 mg in 2 divided doses

Route of admnistration

Oral

Defined daily dose

400 - 800 mg

Dosage regimen

From 200 To 400 mg 2 time(s) per day every day

Loading dose

800 mg

Maintenance dose

400 mg

Detailed description

The minimum effective dose should be employed. This dose should not exceed 6.5 mg/kg/day (calculated from ideal body weight and not actual body weight) and will be either 200 mg or 400 mg per day.

In patients able to receive 400mg daily: Initially 400 mg daily in divided doses. The dose can be reduced to 200 mg when no further improvement is evident. The maintenance dose should be increased to 400 mg daily if the response lessens.

Hydroxychloroquine is cumulative in action and will require several weeks to exert its beneficial effects, whereas minor side effects may occur relatively early. For rheumatic disease treatment should be discontinued if there is no improvement by 6 months. In light-sensitive diseases, treatment should only be given during periods of maximum exposure to light.

Dosage considerations

Each dose should be taken with a meal or glass of milk.

Active ingredient

Hydroxychloroquine

Hydroxychloroquine is a antimalarial agent with have several pharmacological actions which may be involved in their therapeutic effect in the treatment of rheumatic disease, but its role is not known.

Read more about Hydroxychloroquine

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