Hidradenitis suppurativa

Active Ingredient: Bimekizumab

Indication for Bimekizumab

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Bimekizumab is indicated for the treatment of active moderate to severe hidradenitis suppurativa (acne inversa) in adults with an inadequate response to conventional systemic HS therapy.

For this indication, competent medicine agencies globally authorize below treatments:

320 mg every 2 weeks up to Week 16 and every 4 weeks thereafter

For:

Dosage regimens

Subcutaneous, 320 milligrams bimekizumab, once every 2 weeks, 5 doses in total. Afterwards, subcutaneous, 320 milligrams bimekizumab, once every 4 weeks.

Detailed description

The recommended dose for adult patients with hidradenitis suppurativa is 320 mg every 2 weeks up to Week 16 and every 4 weeks thereafter.

Consideration should be given to discontinuing treatment in patients who have shown no improvement by 16 weeks of treatment.

Dosage considerations

Suitable areas for injection include thigh, abdomen and upper arm. Injection sites should be rotated and injections should not be given into psoriasis plaques or areas where the skin is tender, bruised, erythematous, or indurated.

Active ingredient

Bimekizumab

Bimekizumab is a humanised IgG1/Îș monoclonal antibody that selectively binds with high affinity to IL-17A, IL-17F and IL-17AF cytokines, blocking their interaction with the IL-17RA/IL-17RC receptor complex. Elevated concentrations of IL-17A and IL-17F have been implicated in the pathogenesis of several immune-mediated inflammatory diseases including plaque psoriasis.

Read more about Bimekizumab

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