Induction of general anaesthesia

Active Ingredient: Etomidate

Indication for Etomidate

Population group: only adults (18 - 65 years old)

For this indication, competent medicine agencies globally authorize below treatments:

0.3 mg/kg

Route of admnistration

Intravenous

Defined daily dose

3 mg per kg of body weight

Dosage regimen

3 mg per kg of body weight once every day

Detailed description

A dose of 0.3 mg/kg bodyweight given intravenously at induction of anaesthesia, gives sleep lasting from 4 to 5 minutes.

Dosage should be adjusted to the individual patient response and to clinical effects.

Since etomidate has no analgesic action, appropriate analgesics should be used in procedures involving painful stimuli.

Hypnosis can be prolonged by additional injections of etomidate.

Do not exceed a total dose of 60 mg.

Active ingredient

Etomidate

Etomidate is an imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid (GABA) like effects, mediated through GABA-A receptor. The action enhances the inhibitory effect of GABA on the central nervous system by causing chloride channel opening events which leads to membrane hyperpolarization.

Read more about Etomidate

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