Active Ingredient: Quinapril
For the treatment of all grades of essential hypertension. Quinapril is effective as monotherapy or concomitantly with diuretics in patients with hypertension.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
2.5 - 40 mg
From 2.5 To 40 mg once every day
The recommended initial dosage is 10 mg once daily in uncomplicated hypertension. Depending upon clinical response, patient’s dosage may be titrated (by doubling the dose allowing adequate time for dosage adjustment) to a maintenance dosage of 20 mg/day to 40 mg/day given as a single dose or divided into 2 doses. Long-term control is maintained in most patients with a single daily dosage regimen. Patients have been treated with dosages up to 40 mg/day. Take either with or without food. The dose should always be taken at about the same time of day to help increase compliance.
In order to determine if excess hypotension will occur, an initial dosage of 2.5 mg of quinapril is recommended in patients who are being treated with a diuretic. After this the dosage of quinapril should be titrated (as described above) to the optimal response.
In elderly patients and in patients with a creatinine clearance of less than 40 mL/min, an initial dosage in essential hypertension of 2.5 mg is recommended followed by titration to the optimal response.
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