Active Ingredient: Fluorouracil
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
200 - 1,000 mg per m² of body surface area (BSA)
From 200 To 1,000 mg per m² of body surface area (BSA) once every day
5-fluorouracil is commonly used in combination with cisplatin; or cisplatin and epirubicin; or epirubicin and oxaliplatin. Dose varies between 200-1,000 mg/m² body surface per day as continuous intravenous infusion over several days and repeated cyclically depending upon regimen.
For cancers involving lower part of oesophagus, peri-operative chemotherapy with ECF regimen (epirubicin, cisplatin, 5-fluorouracil) is commonly recommended. The recommended dose of 5-fluorouracil is 200 mg/m² body surface per day given as continuous intravenous infusion for 3 weeks and repeated cyclically.
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