Active Ingredient: Conestat alfa
Conestat alfa is indicated for treatment of acute angioedema attacks in adults with hereditary angioedema (HAE) due to C1 esterase inhibitor deficiency.
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
50 - 50 [iU] per kg of body weight
From 50 To 50 [iU] per kg of body weight once every day
Body weight up to 84 kg:
Body weight of 84 kg or greater:
In the majority of cases, a single dose of conestat alfa is sufficient to treat an acute angioedema attack. In case of an insufficient clinical response, an additional dose (50 U/kg body weight up to 4,200 U) can be administered at the discretion of the physician.
Determine the patient’s body weight.
Body weight up to 84 kg:
Volume to be administered (ml) = body weight (kg) times 50 (U/kg) / 150 (U/ml) = body weight (kg) / 3
Body weight of 84 kg or greater:
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