Active Ingredient: Dacarbazine
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
200 - 250 mg per m² of body surface area (BSA)
From 200 To 250 mg per m² of body surface area (BSA) once every day for 5 day(s)
Dacarbazine can be administered as single agent in doses of 200 to 250 mg/m² body surface area/day as an i.v. injection for 5 days every 3 weeks.
As an alternative to an intravenous bolus injection dacarbazine can be administered as a short-term infusion (over 15-30 minutes).
Doses up to 200 mg/m² may be given as a slow intravenous injection. Larger doses (ranging from 200 to 850 mg/m²) should be administered as an i.v. infusion over 15-30 minutes.
Intravenous
850 - 850 mg per m² of body surface area (BSA)
From 850 To 850 mg per m² of body surface area (BSA) once every 21 day(s)
It is also possible to give 850 mg/m² body surface area on day 1 and then once every 3 weeks as intravenous infusion.
Doses up to 200 mg/m² may be given as a slow intravenous injection. Larger doses (ranging from 200 to 850 mg/m²) should be administered as an i.v. infusion over 15-30 minutes.
Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.
