Active Ingredient: Ipilimumab
Ipilimumab as monotherapy is indicated for the treatment of advanced (unresectable or metastatic) melanoma in adults and adolescents 12 years of age and older.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intravenous, 30 milligrams ipilimumab per kilogram of body weight, once every 3 weeks, 4 doses in total.
The recommended induction regimen of ipilimumab is 3 mg/kg administered intravenously over a 90-minute period every 3 weeks for a total of 4 doses. Patients should receive the entire induction regimen (4 doses) as tolerated, regardless of the appearance of new lesions or growth of existing lesions. Assessments of tumour response should be conducted only after completion of induction therapy.
The recommended infusion period is 30 minutes.
Ipilimumab must not be administered as an intravenous push or bolus injection.
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