Active Ingredient: Amlodipine
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 5 milligrams amlodipine, once daily. Afterwards, oral, between 5 milligrams amlodipine and 10 milligrams amlodipine, once daily.
The usual initial dose is 5 mg once daily which may be increased to a maximum dose of 10 mg depending on the individual patient’s response.
In hypertensive patients, amlodipine has been used in combination with a thiazide diuretic, alpha blocker, beta blocker, or an angiotensin converting enzyme inhibitor.
No dose adjustment of amlodipine is required upon concomitant administration of thiazide diuretics, beta blockers, and angiotensin-converting enzyme inhibitors.
Amlodipine used at similar doses in elderly or younger patients is equally well tolerated. Normal dosage regimens are recommended in the elderly, but increase of the dosage should take place with care.
For:
Oral, 2.5 milligrams amlodipine, once daily, over the duration of 4 weeks. Afterwards, oral, between 2.5 milligrams amlodipine and 5 milligrams amlodipine, once daily. The maximum allowed total dose is 5 milligrams amlodipine daily.
The recommended antihypertensive oral dose in paediatric patients ages 6-17 years is 2.5 mg once daily as a starting dose, up-titrated to 5 mg once daily if blood pressure goal is not achieved after 4 weeks. Doses in excess of 5 mg daily have not been studied in paediatric patients.
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