Active Ingredient: Attenuated varicella-zoster virus
Varicella-zoster virus is indicated for prevention of herpes zoster (“zoster” or shingles) and herpes zoster-related post-herpetic neuralgia (PHN).
It is indicated for immunization of individuals 50 years of age or older.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Regimen A: Subcutaneous, 19,400 plaque-forming units attenuated varicella-zoster virus, one dose.
Regimen B: Intramuscular, 19,400 plaque-forming units attenuated varicella-zoster virus, one dose.
Individuals should receive a single dose (0.65 mL).
After reconstitution, 1 dose (0.65 mL) contains: Varicella-zoster virus, Oka/Merck strain, (live, attenuated) not less than 19,400 PFU.
The need for a booster dose is not known.
The vaccine can be injected subcutaneously (SC) or intramuscularly (IM), preferably in the deltoid region.
The vaccine should be administered subcutaneously in patients with severe thrombocytopenia or any coagulation disorder.
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