Non insulin dependent diabetes mellitus type 2

Active Ingredient: Gliclazide

Indication for Gliclazide

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

40-320 mg in 1-2 divided doses daily

Route of admnistration

Oral

Defined daily dose

40 - 320 mg

Dosage regimen

From 20 To 160 mg 2 time(s) per day every day

Detailed description

Adults

The total daily dose may vary from 40-320 mg. The dose should be adjusted according to the individual’s response, commencing with 40-80 mg daily and increasing until adequate control is achieved. A single dose should not exceed 160 mg. When higher doses are required, gliclazide should be taken twice daily and according to the main meals of the day.

In obese patients or those not showing adequate response to gliclazide alone, additional therapy may be required.

Elderly

Plasma clearance of gliclazide is not altered in the elderly and steady state plasma levels can therefore be expected to be similar to those in adults under 65 years. Clinical experience in the elderly to date shows that gliclazide is effective and well tolerated. Care should be exercised however, when prescribing sulfonylureas in the elderly due to a possible age-related increased risk of hypoglycaemia.

Active ingredient

Gliclazide

Gliclazide is a hypoglycaemic sulfonylurea antidiabetic active substance. Gliclazide reduces blood glucose levels by stimulating insulin secretion from the β-cells of the islets of Langerhans.

Read more about Gliclazide

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