Active Ingredient: Gliclazide
For this indication, competent medicine agencies globally authorize below treatments:
Oral
40 - 320 mg
From 20 To 160 mg 2 time(s) per day every day
The total daily dose may vary from 40-320 mg. The dose should be adjusted according to the individual’s response, commencing with 40-80 mg daily and increasing until adequate control is achieved. A single dose should not exceed 160 mg. When higher doses are required, gliclazide should be taken twice daily and according to the main meals of the day.
In obese patients or those not showing adequate response to gliclazide alone, additional therapy may be required.
Plasma clearance of gliclazide is not altered in the elderly and steady state plasma levels can therefore be expected to be similar to those in adults under 65 years. Clinical experience in the elderly to date shows that gliclazide is effective and well tolerated. Care should be exercised however, when prescribing sulfonylureas in the elderly due to a possible age-related increased risk of hypoglycaemia.
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