Active Ingredient: Glucose
Glucose 20% is hypertonic (in vitro tonicity, in a container) and provides a source of calories in a minimal volume of water. Glucose 20% is frequently used in both adults and children to restore blood glucose concentrations in the treatment of hypoglycaemia resulting from insulin excess or from other causes.
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
125 - 3,000 mL
From 125 To 3,000 mL once every day
Dosage of Glucose depends on the age, weight, clinical condition of the patient.
Fluid and acid base balance, serum glucose, serum sodium, and other electrolytes may need to be monitored before and during administration, especially in patients with increased non-osmotic vasopressin release (syndrome of inappropriate antidiuretic hormone secretion, SIADH) and in patients co-medicated with vasopressin agonists due to the risk of hyponatraemia.
Monitoring of serum sodium is particularly important for physiologically hypotonic fluids (in vivo tonicity). Glucose 20 % may become extremely hypotonic after administration due to glucose metabolism in the body.
For the reversal of hypoglycaemic coma. Up to 125ml of a 20% w/v solution.
As an energy source and in carbohydrate depletion. Up to 3 Litres per day dependent on the needs of the patient.
Only to be used under the supervision of a paediatrician.
Glucose 20% must be administered by the intravenous route; it must not be administered by subcutaneous or intramuscular route. Except in the emergency treatment of severe hypoglycaemia, Glucose 20% should be administered via a central vein.
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