Active Ingredient: Ramipril
Incipient glomerular diabetic nephropathy as defined by the presence of microalbuminuria.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 1.25 milligrams ramipril, once daily, over the duration of 2 weeks. Afterwards, oral, between 1.25 milligrams ramipril and 5 milligrams ramipril, once daily. The maximum allowed total dose is 5 milligrams ramipril daily.
Starting dose:
The recommended initial dose is 1.25 mg of ramipril once daily.
Titration and maintenance dose:
Depending on the patient’s tolerability to the active substance, the dose is subsequently increased. Doubling the once daily dose to 2.5 mg after two weeks and then to 5 mg after a further two weeks is recommended.
It is recommended that ramipril is taken each day at the same time of the day.
Ramipril can be taken before, with or after meals, because food intake does not modify its bioavailability.
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