Primary insomnia

Active Ingredient: Melatonin

Indication for Melatonin

Population group: only adults (18 years old or older)

Melatonin is indicated as monotherapy for the short-term treatment of primary insomnia characterised by poor quality of sleep in patients who are aged 55 or over.

For this indication, competent medicine agencies globally authorize below treatments:

2 mg once daily

Route of admnistration

Oral

Defined daily dose

2 - 2 mg

Dosage regimen

From 2 To 2 mg once every day

Loading dose

2 mg

Maintenance dose

2 mg

Detailed description

The recommended dose is 2 mg once daily, 1-2 hours before bedtime and after food. This dosage may be continued for up to thirteen weeks.

Dosage considerations

1-2 hours before bedtime and after food.

Active ingredient

Melatonin

Melatonin is a naturally occurring hormone produced by the pineal gland and is structurally related to serotonin. Physiologically, melatonin secretion increases soon after the onset of darkness, peaks at 2-4 am and diminishes during the second half of the night. Melatonin is associated with the control of circadian rhythms and entrainment to the light-dark cycle. It is also associated with a hypnotic effect and increased propensity for sleep.

Read more about Melatonin

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