Wilson's disease

Active Ingredient: Trientine

Indication for Trientine

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Trientine is indicated for the treatment of Wilson’s disease in adults, adolescents and children ≥5 years intolerant to D-penicillamine therapy.

For this indication, competent medicine agencies globally authorize below treatments:

450-975 mg in 2-4 divided doses daily

Route of admnistration

Oral

Defined daily dose

450 - 975 mg

Dosage regimen

From 112.5 To 243.75 mg 4 time(s) per day every day

Detailed description

The starting dose would usually correspond to the lowest dose in the range and the dose should subsequently be adapted according to the patient’s clinical response.

The recommended dose is between 450 mg and 975 mg per day in 2 to 4 divided doses.

Dosage considerations

It is important that trientine is given on an empty stomach, at least one hour before meals or two hours after meals and at least one hour apart from any other medicinal product, food, or milk.

Active ingredient

Trientine

Trientine is a copper-chelating agent whose principal mechanism of action is to eliminate absorbed copper from the body by forming a stable complex that is then eliminated through urinary excretion. Trientine may also chelate copper in the intestinal tract and so inhibit copper absorption.

Read more about Trientine

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