Active Ingredient: Abciximab
Abciximab is indicated as an adjunct to heparin and acetylsalicylic acid for the short-term (1-month) reduction of the risk of myocardial infarction, in patients with unstable angina, not responding to full conventional therapy who have been scheduled for percutaneous coronary intervention.
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
0.25 mg per kg of body weight
0.25 mg per kg of body weight once every day
The recommended dose of Abciximab is a 0.25mg/kg intravenous bolus immediately followed by a 0.125 microgram/kg/min (to a maximum of 10 microgram/min) continuous intravenous infusion.
For the stabilisation of unstable angina patients, the bolus dose followed by the infusion should be started up to 24 hours prior to the possible intervention and concluded 12 hours after the intervention.
For the prevention of ischaemic cardiac complications in patients undergoing percutaneous coronary intervention, and who are not currently receiving an abciximab infusion, the bolus should be administered 10 to 60 minutes prior to the intervention followed by the infusion for 12 hours.
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