Active Ingredient: Alendronic acid
Alendronic acid is indicated for the treatment of:
For this indication, competent medicine agencies globally authorize below treatments:
Oral
70 - 70 mg
From 70 To 70 mg once every 7 day(s)
The recommended dosage is one 70 mg tablet once weekly.
Patients should be instructed that if they miss a dose of alendronic acid, they should take one tablet on the morning after they remember. They should not take two tablets on the same day but should return to taking one tablet once a week, as originally scheduled on their chosen day.
The optimal duration of bisphosphonate treatment for osteoporosis has not been established. The need for continued treatment should be re-evaluated periodically based on the benefits and potential risks of ‘alendronic acid’ on an individualpatient basis, particularly after 5 or more years of use.
To permit adequate absorption of alendronate:
Alendronic acid must be taken at least 30 minutes before the first food, beverage, or medicinal product of the day with plain water only. Other beverages (including mineral water), food and some medicinal products are likely to reduce the absorption of alendronate.
To facilitate delivery to the stomach and thus reduce the potential for local and oesophageal irritation/adverse experiences:
Oral
10 - 10 mg
From 10 To 10 mg once every day
The optimal duration of bisphosphonate treatment for osteoporosis has not been established. The need for continued treatment should be re-evaluated periodically based on the benefits and potential risks of alendronic acid on an individual patient basis, particularly after 5 or more years of use.
Treatment of osteoporosis in post-menopausal women: The recommended dosage is 10 mg once a day.
Treatment of osteoporosis in men: The recommended dosage is 10 mg once a day.
Treatment and prevention of glucocorticoid-induced osteoporosis: For post-menopausal women not receiving hormone replacement therapy (HRT) with an oestrogen, the recommended dosage is 10 mg once a day.
To permit adequate absorption of alendronic acid: alendronic acid must be taken at least 30 minutes before the first food, beverage, or medication of the day with plain water only. Other beverages (including mineral water), food and some medications are likely to reduce the absorption of alendronic acid.
Patients should receive supplemental calcium and vitamin D if dietary intake is inadequate.
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