Active Ingredient: Mepolizumab
Mepolizumab is indicated as an add-on treatment for adult patients with inadequately controlled hypereosinophilic syndrome without an identifiable non-haematologic secondary cause.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Subcutaneous, 300 milligrams mepolizumab, once every 4 weeks.
The recommended dose of mepolizumab is 300 mg administered subcutaneously once every 4 weeks.
Mepolizumab is intended for long-term treatment. The need for continued therapy should be reviewed at least on an annual basis as determined by physician assessment of the patient’s disease severity and level of symptom control.
Patients who develop life-threatening manifestations of HES should also be evaluated for the need for continued therapy, as mepolizumab has not been studied in this population.
Mepolizumab is for subcutaneous injection only and should be administered by a healthcare professional. It may be injected into the upper arm, thigh, or abdomen.
For doses which require more than one injection, it is recommended that each injection is administered at least 5 cm apart.
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