Invasive candidiasis

Active Ingredient: Anidulafungin

Indication for Anidulafungin

Population group: only adults (18 years old or older)

Treatment of invasive candidiasis in adult patients.

For this indication, competent medicine agencies globally authorize below treatments:

100-200 mg once daily

Route of admnistration

Intravenous

Defined daily dose

100 - 200 mg

Dosage regimen

From 100 To 200 mg once every day

Loading dose

200 mg

Maintenance dose

100 mg

Detailed description

Specimens for fungal culture should be obtained prior to therapy. Therapy may be initiated before culture results are known and can be adjusted accordingly once they are available.

A single 200 mg loading dose should be administered on Day 1, followed by 100 mg daily thereafter.

Duration of treatment should be based on the patient’s clinical response.

Duration of treatment

In general, antifungal therapy should continue for at least 14 days after the last positive culture.

There are insufficient data to support the 100 mg dose for longer than 35 days of treatment.

Active ingredient

Anidulafungin

Anidulafungin is a semi-synthetic echinocandin, a lipopeptide synthesised from a fermentation product of Aspergillus nidulans. Anidulafungin selectively inhibits 1,3-β-D glucan synthase, an enzyme present in fungal, but not mammalian cells.

Read more about Anidulafungin

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