Acute peripheral arterial occlusion

Active Ingredient: Heparin

Indication for Heparin

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

For this indication, competent medicine agencies globally authorize below treatments:

50-100 units/kg

Route of admnistration

Intravenous

Defined daily dose

50 - 100 [iU] per kg of body weight

Dosage regimen

From 50 To 100 [iU] per kg of body weight once every day

Detailed description

Loading dose: 50 units/kg intravenously.

Maintenance: 15-25 units/kg/hour by intravenous infusion, or 100 units/kg 4-hourly by intravenous injection.

Daily laboratory monitoring (ideally at the same time each day, starting 4-6 hours after initiation of treatment) is essential during full-dose heparin treatment, with adjustment of dosage to maintain an APTT value 1.5-2.5 x midpoint of normal range or control value.

Dosage considerations

By continuous intravenous infusion in 5% glucose or 0.9% sodium chloride or by intermittent intravenous injection.

The intravenous injection volume of heparin injection should not exceed 15ml.

As the effects of heparin are short-lived, administration by intravenous infusion is preferable to intermittent intravenous injections.

Active ingredient

Heparin

Heparin is an anticoagulant and acts by inhibiting thrombin and by potentiating the naturally occurring inhibitors of activated Factor X (Xa).

Read more about Heparin

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