Moderate to severe manic episodes associated with bipolar I disorder

Active Ingredient: Haloperidol

Indication for Haloperidol

Population group: only elderly (65 years old or older)

Treatment of moderate to severe manic episodes associated with bipolar I disorder.

For this indication, competent medicine agencies globally authorize below treatments:

1-5 mg in 2 divided doses daily

Route of admnistration

Oral

Defined daily dose

1 - 5 mg

Dosage regimen

From 0.5 To 2.5 mg 2 time(s) per day every day

Detailed description

  • The haloperidol dose may be adjusted according to the patient’s response. Careful and gradual dose up-titration in elderly patients is recommended.
  • The maximum dose in elderly patients is 5 mg/day.
  • Doses above 5 mg/day should only be considered in patients who have tolerated higher doses and after reassessment of the patient’s individual benefit-risk profile.

Treatment withdrawal

Gradual withdrawal of haloperidol is advisable.

Missed dose

If patients miss a dose, it is recommended that they take the next dose as usual, and do not take a double dose.

Active ingredient

Haloperidol

Haloperidol is an antipsychotic belonging to the butyrophenones group. It is a potent central dopamine type 2 receptor antagonist, and at recommended doses, has low alpha-1 antiadrenergic activity and no antihistaminergic or anticholinergic activity.

Read more about Haloperidol

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