Active Ingredient: Mepolizumab
Mepolizumab is indicated as an add-on therapy with intranasal corticosteroids for the treatment of adult patients with severe CRSwNP for whom therapy with systemic corticosteroids and/or surgery do not provide adequate control.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Subcutaneous, 100 milligrams mepolizumab, once every 4 weeks.
The recommended dose of mepolizumab is 100 mg administered subcutaneously once every 4 weeks.
Mepolizumab is intended for long-term treatment. Consideration can be given to alternative treatments in patients who have shown no response after 24 weeks of treatment for CRSwNP. Some patients with initial partial response may subsequently improve with continued treatment beyond 24 weeks.
Mepolizumab is for subcutaneous injection only and should be administered by a healthcare professional. It may be injected into the upper arm, thigh, or abdomen.
For doses which require more than one injection, it is recommended that each injection is administered at least 5 cm apart.
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