Emergency contraception

Active Ingredient: Ulipristal

Indication for Ulipristal

Population group: women, only adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Emergency contraception within 120 hours (5 days) of unprotected sexual intercourse or contraceptive failure.

For this indication, competent medicine agencies globally authorize below treatments:

30mg once

Route of admnistration

Oral

Defined daily dose

30 mg

Dosage regimen

30 mg once every day

Detailed description

The treatment consists of 30mg to be taken orally as soon as possible, but no later than 120 hours (5 days) after unprotected intercourse or contraceptive failure. It can be taken at any time during the menstrual cycle. If vomiting occurs within 3 hours of the tablet intake, another 30mg should be taken.

If a woman’s menstrual period is late or in case of symptoms of pregnancy, pregnancy should be excluded before the tablet is administered.

Dosage considerations

It can be taken with or without food.

Active ingredient

Ulipristal

Ulipristal is an orally-active synthetic selective progesterone receptor modulator which acts via high-affinity binding to the human progesterone receptor. When used for emergency contraception the mechanism of action is inhibition or delay of ovulation via suppression of the luteinising hormone (LH) surge. Pharmacodynamic data show that even when taken immediately before ovulation is scheduled to occur (when LH has already started to rise), ulipristal acetate is able to postpone follicular rupture for at least 5 days.

Read more about Ulipristal

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