Prostate cancer

Active Ingredient: Goserelin

Indication for Goserelin

Population group: men, only adults (18 years old or older)

Treatment of prostate cancer in the following settings:

  • In the treatment of metastatic prostate cancer where goserelin has demonstrated comparable survival benefits to surgical castrations.
  • In the treatment of locally advanced prostate cancer, as an alternative to surgical castration where goserelin has demonstrated comparable survival benefits to an anti-androgen.
  • As adjuvant treatment to radiotherapy in patients with high-risk localised or locally advanced prostate cancer where goserelin has demonstrated improved disease-free survival and overall survival.
  • As neo-adjuvant treatment prior to radiotherapy in patients with high-risk localised or locally advanced prostate cancer where goserelin has demonstrated improved disease-free survival.
  • As adjuvant treatment to radical prostatectomy in patients with locally advanced prostate cancer at high risk of disease progression where goserelin has demonstrated improved disease-free survival.

For this indication, competent medicine agencies globally authorize below treatments:

3.6 mg once every 28 days

Route of admnistration

Subcutaneous

Defined daily dose

3.6 - 3.6 mg

Dosage regimen

From 3.6 To 3.6 mg once every 28 day(s)

Detailed description

One 3.6 mg depot of goserelin injected subcutaneously into the anterior abdominal wall, every 28 days.

Active ingredient

Goserelin

Goserelin is a synthetic analogue of naturally occurring LHRH. On chronic administration goserelin results in inhibition of pituitary LH secretion leading to a fall in serum testosterone concentrations in males and serum estradiol concentrations in females.

Read more about Goserelin

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