Active Ingredient: Ixekizumab
Taltz is indicated for the treatment of adult patients with active ankylosing spondylitis who have responded inadequately to conventional therapy.
Taltz is indicated for the treatment of adult patients with active non-radiographic axial spondyloarthritis with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI) who have responded inadequately to nonsteroidal anti-inflammatory drugs (NSAIDs).
For this indication, competent medicine agencies globally authorize below treatments:
For:
Subcutaneous, 160 milligrams ixekizumab, 1 one dose, over the duration of 4 weeks. Afterwards, subcutaneous, 80 milligrams ixekizumab, once every 4 weeks.
The recommended dose is 160 mg by subcutaneous injection at week 0, followed by 80 mg every 4 weeks.
Consideration should be given to discontinuing treatment in patients who have shown no response after 16 to 20 weeks of treatment. Some patients with initially partial response may subsequently improve with continued treatment beyond 20 weeks.
No dose adjustment is required in subjects aged ≥65 years. There is limited information in subjects aged ≥75 years.
If possible, areas of the skin that show psoriasis should be avoided as injection sites.
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