Active Ingredient: Indinavir
Indinavir is indicated in combination with antiretroviral nucleoside analogues for the treatment of HIV-1 infected adults.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
2,400 - 2,400 mg
From 800 To 800 mg 3 time(s) per day every day
The recommended dose of indinavir is 800 mg orally every 8 hours.
Data from published studies suggest that indinavir 400 mg in combination with ritonavir 100 mg, both administered orally twice daily, may be an alternative dosing regimen. The suggestion is based on limited published data.
A dose reduction of indinavir to 600 mg every 8 hours should be considered when administering itraconazole or ketoconazole concurrently.
For optimal absorption, indinavir should be administered without food but with water 1 hour before or 2 hours after a meal. Alternatively, indinavir may be administered with a low-fat, light meal.
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