Active Ingredient: Ezetimibe
Ezetimibe is indicated to reduce the risk of cardiovascular events in patients with coronary heart disease (CHD) and a history of acute coronary syndrome (ACS) when added to ongoing statin therapy or initiated concomitantly with a statin.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 10 milligrams ezetimibe, once daily.
The patient should be on an appropriate lipid lowering diet and should continue on this diet during treatment with ezetimibe.
The recommended dose is 10 mg daily. If as dose is missed, take the missed dose as soon as possible. Do not double the next dose.
For incremental cardiovascular event reduction in patients with coronary heart disease and ACS event history, ezetimibe 10 mg may be administered with a statin with proven cardiovascular benefit.
When ezetimibe is added to a statin, either the indicated usual initial dose of that particular statin or the already established higher statin dose should be continued. In this setting, the dosage instructions for that particular statin should be consulted.
Assess LDL-C when clinically appropriate, as early as 4 weeks after initiating ezetimibe.
In patients taking a bile acid sequestrant, administer ezetimibe at least 2 hours before or 4 hours after the bile acid sequestrant.
Ezetimibe can be administered at any time of the day, with or without food.
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