Active Ingredient: Mercaptamine
Mercaptamine is indicated for the treatment of corneal cystine crystal deposits in adults and children from 2 years of age with cystinosis.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Ophthalmic, 1 drops mercaptamine, 4 times daily.
The recommended dose is one drop in each eye, 4 times a day during waking hours. The recommended interval between each instillation is 4 hours. The dose could be decreased progressively (to a minimum total daily dose of 1 drop in each eye) depending on the results of ophthalmic examination (such as, corneal cystine crystal deposits, photophobia).
If the patient misses an instillation, the patient should be told to continue the treatment with the next instillation.
The dose should not exceed 4 drops a day in each eye.
The accumulation of corneal cystine crystals increases if mercaptamine is discontinued. The treatment should not be stopped.
Mercaptamine may be used in paediatric patients from 2 years of age at the same dose as in adults.
The safety and efficacy of mercaptamine in children aged less than 2 years has not been established. No data are available.
To avoid sticky eyes in the morning, the patient should be advised to apply the last drop of the day at least 30 minutes before going to bed.
To prevent contamination of the dropper tip and solution, care must be taken not to touch the eyelids, surrounding areas, or other surfaces with the dropper tip of the dropper bottle.
In case of concomitant therapy with other topical ocular medicinal products, an interval of ten minutes should be allowed between successive applications. Eye ointments should be administered last.
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